Position located in Boston, MA

Responsibilities of the Genome Engineer:

• Design, innovate and iterate: DNA assembly, integration, editing and screening.
• Build enabling molecular and cellular tools.
• Perform DNA/RNA transfections and/or viral transductions.
• Quantify genome editing events using various molecular assays.
• Improve the state of the art in CRISPR-guided precision genome editing.
• Data analysis, figure generation and timely reporting of results.
• Present findings at small forums and R&D meetings.

Requirements of the Genome Engineer:

• PhD in synthetic biology, bioengineering, molecular biology, genetics or related field is required, or 2+ years hands-on expertise in genetics and genomic manipulation.
• Solid understanding and hands-on experience with current precision editing techniques, covering the design, optimization and verification of edits made with CRISPR-Cas9, Base Editors, or nicking-based methods.