Located in Boston, MA

Responsibilities of the Principal Scientist, Mass Spectrometry:

• Will develop and qualify highly sensitive, reliable LCMS methods for the rapid and accurate analysis of biologic, viral vector, and RNA modalities.
• Perform in-depth mass-spec and biophysical characterization using state-of-the-art equipment.
• Identify emerging practices and drive scientifically innovative method development.
• Troubleshoot assays and apply design of experiments (DOE) and other systematic and statistical approaches to method development, as needed.
• Mentor and provide scientific expertise to the analytical sciences team.
• Represent the analytical sciences team on cross-functional projects and effectively communicate results, progress and plans.

Requirements of the Principal Scientist, Mass Spectrometry:

• Ph.D. in Biochemistry, Chemistry, Biological Engineering, or a related field.
• Must have 3+ years performing mass-spec and biophysical characterization in support of biologic therapies.
• Must have experience with LC/MS assays and HPLC/UPLC analysis of biologics or viral vector therapeutics.