Job ID: #8933

Principal Scientist, Structural Biology

Boston, MA
Science Science
Research & Development

 

Responsibilities of the Principal Scientist, Structural Biology:

  • Lead the scientific, technical, and operational aspects of structural biology for drug discovery programs
  • Lead efforts in parallel including X-ray, NMR, and Cryo-EM with a clear goal of delivering novel and protein structure with small molecules
  • Supervise a team of Scientists and Research Associates, as well as manage the design of protein constructs and protein production to support the assay development
  • Manage external resources to ensure delivery of high-quality protein structural information, efficient recombinant protein design, protein expression, protein purification, crystallization, data collection, and refinement

Requirements of the Principal Scientist, Structural Biology:

  • Ph.D. degree in structural biology or related discipline with at least 5 years of industry experience
  • •Proven ability to design and troubleshoot constructs for crystallization, solve structures for technically challenging proteins, and co-complex of small molecules with target proteins
  • Demonstrated track record of success in structure-enabled drug discovery programs
  • Exceptional interpersonal and communication skills, and the ability to work seamlessly with multiple drug discovery teams and provide structure related support at all stages of the project

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