Job ID: #9528

Senior Scientist, Bioinformatics (NGS)

Cambrige, MA
Science Science
Research & Development

Position located in Cambridge, MA


Responsibilities of the Senior Scientist, Bioinformatics (NGS):

  • Develop and implement bioinformatics pipelines and algorithms for the analysis of plasmid sequencing data, ensuring accuracy, efficiency, and reproducibility.
  • Perform quality control assessments of sequencing data, identify and troubleshoot issues, and provide recommendations for process improvements.
  • Utilize existing bioinformatics tools and software to analyze and annotate plasmid sequences, identifying genetic variations, gene functions, and potential functional implications.
  • Collaborate closely with the molecular biology and sequencing teams to design experiments, provide guidance on sample preparation, and optimize sequencing protocols.
  • Contribute to the development and improvement of data analysis workflows, incorporating new technologies and methodologies as appropriate.
  • Stay up-to-date with the latest advancements in bioinformatics and genomics research, proactively applying new knowledge to enhance data analysis capabilities.


Requirements of the Senior Scientist, Bioinformatics (NGS):

  • PhD degree in Bioinformatics, Computational Biology, Genomics, or a related field.
  • 3+ years industry experience working with NGS data. Nanopore experience is strongly preferred.
  • Strong understanding of molecular biology concepts, genomics, and genetics, particularly in the context of plasmids.
  • Proficiency in programming languages commonly used in bioinformatics, such as Python, R, or Perl.
  • Experience with bioinformatics tools, databases, and software packages commonly used for sequence analysis (e.g., BLAST, Bowtie, SAMtools, BEDTools).
  • Familiarity with next-generation sequencing (NGS) technologies and data analysis pipelines.

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