Job ID: #9490

Sr. Scientist – Bioinformatics

Cambridge, MA
Science Science
Bioinformatics / Biostatistics

Position located in Cambridge, MA


Responsibilities of the Sr. Scientist – Bioinformatics:

  • Develop computational tools to design and select UTR sequences to improve the expression level and stability of mRNAs, for example, through machine learning or secondary structure engineering.
  • Develop algorithms to optimize coding sequence of target genes.
  • Identify candidate enzymes from microbial genomic database to facilitate mRNA production and modification process development.
  • Rational design of mutations to improve the performance of tool enzymes.
  • Develop computational pipelines to analyze high throughput screening data which may involve single cell sequencing analysis.
  • Build analytical infrastructure to support wet lab scientists on data analysis which may involve imaging analysis.


Requirements of the Sr. Scientist – Bioinformatics:

  • Ph.D. in Bioinformatics, Computational Biology, or a related field, with 5+ years industry experience.
  • Proven expertise in mRNA biology, or single-cell RNA sequencing (RNAseq), with a track record of handling and analyzing large-scale datasets.
  • Strong programming skills in various computer languages and experience with database management.
  • Experience with machine learning approaches and their application to biological problems.
  • Excellent communication and interpersonal skills, with experience leading teams and managing stakeholders.
  • Ability to work collaboratively in a fast-paced team environment, and to provide strategic direction to the team.


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