Position located in Boston, MA

*20 hours per week to start*

Position Summary:

We are seeking a Scientist or Senior Scientist with experience in in vivo pharmacology and next-generation sequencing (NGS) to support preclinical research programs. The ideal candidate will have hands-on experience working with animal tissue samples and applying NGS or genomic sequencing approaches to characterize biological responses to drug candidates.

Responsibilities:

• Design and execute in vivo pharmacology studies to evaluate drug efficacy, pharmacodynamics, and mechanisms of action.
• Collect, process, and analyze animal tissue samples from preclinical studies.
• Apply NGS-based approaches to analyze gene expression, genomic, or transcriptomic changes in tissue samples.
• Collaborate with bioinformatics, molecular biology, and discovery teams to interpret sequencing data.
• Develop and optimize tissue processing, RNA/DNA extraction, and sequencing workflows.
• Analyze and present experimental results to cross-functional project teams.
• Contribute to study design, data interpretation, and preparation of reports and presentations.
• Maintain accurate experimental records and ensure studies are conducted in accordance with applicable laboratory and regulatory standards.

Requirements:

• Ph.D. or equivalent advanced degree in Pharmacology, Biology, Molecular Biology, Genetics, or a related discipline.
• Industry or academic experience in in vivo pharmacology/preclinical research.
• Hands-on experience with NGS and/or transcriptomic/genomic analysis.
• Experience working with animal tissues and samples from in vivo studies.
• Familiarity with RNA/DNA isolation, library preparation, sequencing technologies, and/or sequencing data analysis.
• Strong experimental design, data analysis, and communication skills.