Job ID: #9753

Scientist (Immuno-oncology)

Rochester, MN
Science Science
Research & Development

Position located in Rochester, MN


Responsibilities of the Scientist (Immuno-oncology):

  • Design and perform independent experiments in tissue culture, and viral infections in rodent tumor models. Execute experiments from set up to take down, and downstream cellular analysis.
  • The position will play a critical role in the generation of new vector constructs and troubleshooting the vector expression in CAR T cells.
  • Design, generate and characterize CAR or other constructs for genetically modified T cells.
  • Independently design and lead pre-clinical in life studies including downstream analysis.
  • Collect, analyze, and present scientific data to the research and management teams; with proposed next steps.
  • Self-motivated and driven to work independently and collaboratively as part of a team.
  • Coordinate research efforts and make key scientific and technical contributions for the strategic development of cross-functional projects.
  • The candidate will perform independent experimental research but will work in close collaboration with the rest of the scientific team in a highly cross-functional and project-oriented environment.


Requirements of the Scientist (Immuno-oncology):

  • PhD or Master degree in Immunology or a related field with a minimum of 3 years of industry or academic experience in immunology and in vivo oncology or pharmacology.
  • Exceptional laboratory skills, with demonstrated proficiency in the development and execution of primary immune cell assays (T cell and/or myeloid cell).
  • Deep understanding of adaptive immunity including T cell, B cell, myeloid or dendritic cell biology.
  • Working knowledge of all stages of CAR design and virus generation.


Valued Complementary Skills:

  • T cell activation assay (Mouse or human)
  • T cell memory response recall assays: ELISPOT
  • Immunohenotyping: Multiplex and tetramer analysis
  • Immuno histochemistry, with focus on T cell markers (Multiplex)
  • RNAscope
  • Handling and processing human PBMC samples
  • Processing of mouse spleen, Lymph nodes for downstream analysis
  • Additional preferred qualifications: RNAseq analysis, Exome sequencing

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    Commonwealth Sciences is a professional recruiting firm specializing in Life Science, Medical Device, and Engineering Technologies. We unite industry professionals with exciting career opportunities by leveraging our technical expertise, advanced recruiting tools and years of staffing experience. CWS works with a variety of disciplines and levels from Research Associates to Scientists, Engineers, Managers and Directors. Our clients value the basic integrity, customer service and industry expertise that defines our organization.